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Jinqian Li, STEaPP Alumni, reflects on her MPA Experience at UCL

By leonie.dunn, on 18 November 2024

Head shot of Alumni Jinqian Li

My academic journey in the Master of Public Administration (MPA) in Digital Technologies and Policy at University College London has been truly enriching. The programme has equipped me with robust analytical skills to understand cutting-edge technologies and develop evidence-based policies that address their societal implications.

The curriculum was thoughtfully structured to provide hands-on experience in policy development across multiple domains. The simulated multilateral negotiations were particularly valuable, where we represented different nations to address urgent technological and social challenges. These exercises strengthened our ability to analyse complex issues efficiently, identify key priorities, and develop practical policy solutions under time constraints while honing our diplomatic and negotiation skills.

The programme’s emphasis on real-world application culminated in our group project, where we collaborated with industry partners to address contemporary challenges. Through this experience, I developed essential skills in teamwork, professional communication, and data analysis. Our research on IoT privacy frameworks with the Information Commissioner’s Office across China, the UK, and Japan led to a presentation at the PETRAS conference in London, where engaging with international academics helped refine our policy recommendations.

A significant achievement during my MPA studies was publishing an op-ed in the AI&Society journal, developed under Dr. Jean-Christophe Mauduit’s guidance. The piece examined the implications of police use of facial recognition technology in the UK, focusing on transparency and bias concerns. Additionally, my analysis of Weibo’s role in China’s digital landscape, written for another module focusing on technology complex, supported my successful application to the University of Cambridge’s MPhil programme.

The supportive environment at UCL really enhanced the academic experience. The guidance from faculty members and collaboration with fellow international students created a constructive learning atmosphere that facilitated both professional and personal growth. It’s somewhere I would always love to return to share life updates and exchange ideas, both academic and personal.

For those keen to shape the future of technology policy and make a meaningful impact on society, I wholeheartedly recommend exploring UCL’s Department of Science, Technology, Engineering and Public Policy (STEaPP). Whether you’re fascinated by emerging technologies technically/ethically, deeply committed to sustainability, or passionate about bridging the gap between innovation and public good, STEaPP offers brilliant pathways to help you achieve your aspirations.

Author: Jinqian Li, STEaPP Alumni. MPA Digital Technologies and Policy 2022-2023.

Seaweed revolution – how can we support the emergent seaweed industry to deliver a more sustainable future?

By luis.lacerda, on 19 July 2024

As the new Government comes into power, the UK’s ambition to position itself as a global clean Energy Superpower has been renewed. Government has expressed the need to invest in a new industrial strategy where sustainability goals are critical to deliver economic growth and achieve clean energy by 2030. This includes investing in new jobs and technologies and exploring responsible ways to utilise the UK’s naturally available bioresources.

Seaweed (macroalgae) has a pivotal role to play in delivering ambitions on clean energy, and incubation and support for this emerging industry must feature in the future industrial strategy to unlock the transformative potential it can offer. Seaweed-derived bioproducts can be used to displace fossil fuel-derived compounds across multiple sectors, including plastics, fabrics, fuels, pharmaceuticals, and the nutraceuticals industries. Furthermore, seaweed can capture more carbon than it releases to the atmosphere (carbon sink), contributing as a natural tool to tackle climate change.

To unlock these benefits, we must scale up seaweed biorefineries in the UK, but there are several engineering, bioscience and societal challenges currently holding this back. Tackling these challenges and demonstrating the feasibility and potential of scaled-up seaweed biorefineries in the UK, is the focus of important research currently being conducted by Dr Emily Kostas at the new Manufacturing Futures Lab at UCL East. It is envisioned that this research will encourage Government to support UK seaweed aquaculture and increase the availability of this versatile and sustainable feedstock.

Despite important efforts to map and characterize opportunities for seaweed farming across the UK [1],[2], there has been no strong policies and support at the necessary scale to realize the ambitions set above. Numerous UK companies are, in fact, currently importing seaweed from abroad (Norway and the Faroe Islands) due to the lack of a constant supply and adequate amount of seaweed biomass that is currently available here in the UK, which clearly demonstrates that there is demand and that the market is ready for this transition.

We believe there is an opportunity to sink carbon and support green energy domestically by promoting the scale-up of seaweed-derived bioproducts, biofuels, biochemicals and biomaterials that have been manufactured from UK farmed seaweed.

Therefore, we have identified three key recommendations for policy action going forward:

  • Build on existing evidence base of suitable areas for sustainable aquaculture[3] and monitor the regional landscape availability and production of native seaweed feedstocks; this would ensure a constant supply and will meet the demand for a future UK bioeconomy.
  • Design and deliver a new regulatory and policy framework that promotes sustainable seaweed farming and cultivation in the UK, based on solid, sustainable and responsible planning on how to best manage marine environments[4],[5].
  • Work with coastal communities and stakeholders to explore how to meaningfully develop a plan to create job security whilst protecting natural resources and landscape.

Seaweed can provide a fresh start to ignite a new UK industrial strategy and contribute to achieving the ambitious goals of delivering clean energy by 2030 and production of alternative and sustainable products. The ability to do so rests on how effectively we can bolster the UK’s aquaculture in the years ahead.

References

[1] https://thefishsite.com/articles/initiative-aims-to-take-uk-seaweed-sector-to-the-next-level

[2]  https://www.carymor.wales/seaweed/seaweed-farming-in-the-uk

[3] Identification of strategic areas of sustainable aquaculture production in English waters: Final Report

[4] https://www.gov.uk/government/collections/marine-planning-in-england

[5] https://www.gov.scot/policies/marine-planning/

Unleashing the economic potential of UK manufacturing

By a.tacu, on 2 May 2024

Image of speaker presentingManufacturing has a pivotal role to play in building a thriving future UK economy which is resilient and can meet many of the increasingly pressing challenges facing UK society.  

But is this fundamental role fully understood by those outside the world of manufacturing? Attending ‘The Future of UK Manufacturing’ event earlier this month has prompted me to reflect on this question.  

Common cross-sectoral challenges and potential solutions 

Recent policy developments such as the UK’s Advanced Manufacturing Plan supported by £4.5 billion of funding for strategic manufacturing sectors, the Net Zero Strategy and the UK Net Zero Research and Innovation Framework point to the increasing awareness of the importance of manufacturing for the UK economy in recent years.  

While this is welcome, a number of challenges continue to hamper the ability of manufacturing to realise its true economic potential. 

One of the key apparent challenges is that, despite the fact that the UK is a global leader in innovation and research, this does not fully translate into economic value through industrial activity [1]. For example, in terms of number of research publications, the UK surpasses the US in per capita terms, but it lags behind in translating scientific knowledge into commercial success. A telling example is that the word ‘manufacturing’ is only mentioned once in the ‘Science and Technology Framework’, which risks creating the perception that the onus is on industry when it comes to scaling up new technologies. 

Although a constant stream of fundamental research is a crucial part of the innovation ecosystem, the ability to scale up lab-based demonstrations needs to become an equally prominent part of how research is undertaken in the UK to set the right conditions for success. Lessons can be learned from the example of the Oxford-AstraZeneca Covid-19 vaccine where the parallel research in immunology and in manufacturing, supported by the Vax-Hub, contributed to the speedy Covid-19 vaccine rollout.  

Another significant challenge for the UK manufacturing community is skills gaps, which amounts to between £7.7 and £8.3 billion in lost annual economic output [2]. Part of the difficulty in attracting talent to manufacturing careers is that manufacturing jobs are still associated with a traditional view of manufacturing roles as being manual and poorly paid. A study led by InterAct suggests that these perceptions can be changed by focusing on levers which have the potential to attract people to manufacturing careers such as flexibility and being part of the solution to many of the health-related, environmental and economic issues we are facing. 

Which leads us to one of the recurring themes that emerged from the discussions held during the event – the importance of storytelling and narrative setting. There was agreement that the UK manufacturing community should challenge outdated perceptions and create a positive narrative about the role of manufacturing that cuts across sectors and is clearly communicated to policymakers and those outside the world of manufacturing. Coalescing around a common strong narrative can support with ensuring manufacturing remains high on the policymakers’ agendas and can attract the skilled people it needs.  

So, what could this narrative be? One of the workshop sessions explored this exact question. A strong narrative should show how manufacturing can be at the forefront of creating good quality jobs and be a fundamental part of the UK’s future economic prosperity and national security.  

Early-stage R&D, which underpins manufacturing innovation, requires continued long-term funding support as businesses are often risk-averse and not incentivised to invest sufficiently at that stage. The Engineering & Physical Sciences Research Council (EPSRC) has been responding to this need through its manufacturing for the future research funding programmes, which is very welcome. I am left convinced that prioritising this type of investment is more important than ever and that, over the long term, these investments will more than pay for themselves in value returned to the UK. 

Context 

The EPSRC together with the High Value Manufacturing Catapult and the Institute for Manufacturing at the University of Cambridge organised ‘The Future of UK Manufacturing’ event in Sheffield. The event brought together academics, policymakers, innovation agencies and industry to review the current UK manufacturing landscape and to look ahead to future research and innovation priorities and opportunities. I attended this event as Policy Adviser for Vax-Hub Sustainable, one of the manufacturing research hubs funded by EPSRC and co-led by UCL Biochemical Engineering and the University of Oxford.   

Author’s note 

Written by Anca Tacu, Policy Impact Unit. With thanks to Jen Reed, Head of Policy Impact Unit, for her valuable contributions.  

References 

[1] Cambridge Industrial Innovation Policy. 2024. UK Innovation Report 2024. Available at: https://www.ciip.group.cam.ac.uk/innovation/the-uk-innovation-report-2024/  

[2] Policy Connect. 2023. Upskilling Industry: Manufacturing productivity and growth in England. Available at: https://www.policyconnect.org.uk/research/upskilling-industry-manufacturing-productivity-and-growth-england  

The importance of collaboration to advance digital health

By luis.lacerda, on 27 March 2024

Earlier this month the Government announced a £3billion+ package to update fragmented and outdated IT systems across the NHS and transform the use of data to ease administrative burdens. That same week, the Policy Impact Unit (PIU) hosted a roundtable on digital health in the UK, bringing together colleagues from across UCL (see co-authors) as well as visiting researchers from the FioCruz Oswaldo Cruz Foundation in Brazil.

FioCruz is a federal public research foundation working with academic autonomy under the Ministry of Health of Brazil which was responsible for coordinating the COVID-19 vaccination campaign. The Brazilian delegation were keen to hear about UK experiences on health digitisation, challenges and opportunities, as well as developing a deeper understanding of the context and evaluation of several commitments agreed under the Brazil-UK High-Level Strategic Dialogues from 2020, some of which focussed on health cooperation and were funded by the Official Development Assistance (ODA) [1].

The main challenges discussed in the meeting, in relation to the digitalisation of the NHS, were systems’ interoperability, training and workforce capacity. Although there has been a push towards the adoption of federated data platforms (FDP), which will sit across NHS trusts and integrated care systems allowing them to connect data they already hold in a secure and safe environment, these are still disjointed and connecting them relies on platform providers talking to each other, which often does not happen.

Common challenges: interoperability, training and workforce capacity

The adoption of new digital health approaches is also reliant on having trained healthcare professionals to understand the power of data and new technologies. Particularly in primary care and GPs it is essential to have digitally literate colleagues that can engage communities, be clear and transparent about how health data is used and input it correctly to build FDPs that can be further used for research and to invest on the health of the nation[2]. Programmes like the NHS “Developing healthcare workers’ confidence in artificial intelligence” and inclusive digital healthcare are important, because there is a risk that ambitions to digitise the NHS, which are well intended, could exacerbate existing health inequalities and exclude some groups.

Incidentally, there is still a lack of progress to de-identify General Practice data and address low levels of confidence in new technologies among diverse communities – such as highlighted in the Health and Social Care Committee’s recent evaluation. Trust can be undermined as is the societal buy-in needed to deliver on ambitions for a more digital NHS.

Opportunities and way forward: innovation in regulatory mechanisms

On the flipside, there is an opportunity to bring people in early on to discussions on how AI tools are being used in medical devices, and how to properly manage the balance of risk and benefits such technologies may bring. The recent launch of the UK Regulatory Science and Innovation Networks was discussed, as well as the launch of a MHRA roadmap to create a framework for medical devices in the UK. Patients, researchers and industry representatives being included in this process, and being clear about how data can be used for the purposes of research, poses a great opportunity to bring real impact to clinical practice in terms of diagnosis, treatment, and monitoring of diseases.

Including other global partners in this conversation is essential given the importance of sharing learnings in different contexts, but also given the increasingly important role of international recognition in the medical domain as a factor to evidence impact. Specifically for global issues such as AI and post-market surveillance, where it is very difficult for regulators to know how new tools will perform before they are deployed, there is now a chance to have new standards emerge to shape digital health strategies across countries. We hope that visits like this inspire colleagues to work collaboratively and look forward to hearing from FioCruz how their visit is supporting Brazilian policy decisions on the development of digital health strategies.

Authors Note

Written by Dr. Luís Lacerda, Policy Impact Unit and co-authored by Professor Amitava Banerjee, UCL Institute of Health Informatics, Professor Derek Hill, UCL Dept of Medical Physics & Biomedical Engineering and Professor Patty Kostkova, UCL Institute for Risk & Disaster Reduction.

References

[1] For a list of projects funded under the scheme, please visit https://devtracker.fcdo.gov.uk/

[2] A particular good example was the COVID-19 registry where data such as vaccination rates, long-covid reports were put together in the same place and from different countries.

What can we do to decrease the cost of advanced cancer therapies and make them available for all?

By luis.lacerda, on 9 February 2024

There are 3 million people living with cancer in the UK, predicted to rise to 4 million by 2030[1]. Different societal groups are affected differently, in particular ethnic minorities who experience poorer outcomes[2]. Health inequalities are complex and their root causes diverse, including the fact that some cancers are more prevalent in specific communities[3]. Advanced research on targeted and personalised treatments can therefore bring hope to improve outcomes in the future and to “close the gap” in the access to cancer care. But how can these be made more affordable and included in holistic government strategies to manage cancer care?

Illustration of two people, two pill bottles and two DNA strandsAt UCL, the Future Targeted Healthcare Manufacturing Hub (FTHM Hub), which brings together academics, manufacturers, and policymakers, has been addressing manufacturing, business, and regulatory challenges to ensure that new targeted biological medicines can be developed quickly and manufactured at a cost affordable to society. This includes innovative research on the manufacture of promising cancer therapies ranging from Chimeric antigen receptor T-cell (CAR-T) therapies through to targeted drug therapies such as antibody-drug conjugates and cancer vaccines. The Hub engages with and supports several clinical groups at UCL that develop advanced therapy medicinal products (ATMPs), some of which have been commercialised or are being translated into the clinic.

The FTHM Hub’s work also includes more fundamental research into optimising manufacturing by innovating processes and finding new ways of reducing production costs of these therapies. Examples of this activity include manufacturing autologous CAR-T therapy at the patient’s bedside or in an automated “GMP-in-a box” system[4], which can bring about benefits in terms of cost reductions, accelerating bench-to-bedside innovation, and mitigate risks that are generated by market shortages[5].

The Hub has worked closely with healthcare specialists and regulatory authorities to analyse how CAR-Ts and other high-cost therapies affect NHS England’s ability to resource other health services. It has conducted detailed supply chain economics analysis to identify key cost of goods drivers for CAR-T therapies, supply chain optimisation, and to assess the risk-reward trade-offs between centralised and distributed manufacture.

The recent agreement reached between the Department of Health and Social Care (DHSC), NHS England and the Association of the British Pharmaceutical Industry (ABPI) on a voluntary scheme for branded medicines pricing, access and growth is a welcomed programme to explore how industry and government can better work to support the delivery of new advanced treatments for cancer, but this is not enough.

Furthermore, and for this important work to continue, investment and support on advanced manufacturing is required to understand possible implementation challenges of novel options such GMP-in-a-box in clinical settings. The new UK’s life sciences manufacturing funding to build resilience for future health emergencies is a good opportunity to do this to expand on the FTHM Hub’s work and ensure every patient living with cancer will have accessibility of treatment irrespective of geographical location.

In addition, time and cost of travel to specialised centres can pose an economic burden to patients and carers due to disparities in cancer care. New centres will also need dedicated staff to help deliver advanced therapies and the FTHM Hub is also training a new generation of professionals to enable rollout of those to patients.

In the week that marks World Cancer Day, the FTHM Hub continues to develop important work to treat patients with cancer and it is our hope at the Policy Impact Unit that we can work towards imagining new futures together, close the care gap, and bring better outcomes for all of those living with cancer.

 

References

[1] https://www.macmillan.org.uk/dfsmedia/1a6f23537f7f4519bb0cf14c45b2a629/11424-10061/Macmillan%20statistics%20fact%20sheet%20February%202023

[2] Martins, T., Abel, G., Ukoumunne, O.C. et al. Ethnic inequalities in routes to diagnosis of cancer: a population-based UK cohort study. Br J Cancer 127, 863–871 (2022). https://doi.org/10.1038/s41416-022-01847-x

[3] Delon, C., Brown, K.F., Payne, N.W.S. et al. Differences in cancer incidence by broad ethnic group in England, 2013–2017. Br J Cancer 126, 1765–1773 (2022). https://doi.org/10.1038/s41416-022-01718-5

[4] Pereira Chilima, T. & S. Farid. 2019. ‘A roadmap to successful commercialization of autologous CAR T-cell products with centralized and bedside manufacture.’ Cell Gene Therapies VI 73. Comisel, R. 2022. Decisional Tools for Supply Chain Economics of Cell and Gene Therapy Products. Diss. UCL (University College London).

[5] Bicudo, E. & I. Brass. 2023, ‘Advanced therapies, hospital exemptions & marketing authorizations: the UK’s emerging regulatory framework for point-of-care manufacture’ Cell and Gene Therapy Insights 9(1), 101-120.